32 Actors Who Popped Up On Scrubs

I cannot count how many times Scrubs has come up when discussing the best TV sitcoms of all time. Over the course of nine seasons (and two networks), the Zach Braff-led medical comedy introduced audiences to some of the most iconic and endearing small-screen characters of the past 25 years, as well as some legendary celebrity guests. With Academy Award winners, Star Wars alumni, and on-the-rise comedians, Sacred Heart Hospital was a hopping place when these 32 actors popped up on Scrubs.

Brendan Fraser

Though Brendan Fraser is best known for roles in movies like The Mummy, The Whale, and Encino Man, the Oscar winner played a small yet pivotal role as Ben Sullivan on Scrubs. Dr. Cox’s (John C. McGinley) brother-in-law, Ben was at the center of several of the best episodes of Scrubs as well as one of the most emotional TV moments of all time. Seriously, Ben is one of the best characters to ever appear on the show, which is saying a lot.

Michael J. Fox

One of several Spin City cast members to show up on Scrubs, Michael J. Fox appeared in a pair of episodes during the show’s third season. Taking on the role of Dr. Kevin Casey, a confident and talented doctor and surgeon dealing with obsessive-compulsive disorder.

Ryan Reynolds

Before he was leading some of the best Marvel movies and showing up in great romantic comedies, Ryan Reynolds had a one-off appearance on Scrubs. Showing up in the show’s second season, Reynolds played Spence, J.D. (Zach Braff) and Turk’s (Donald Faison) college friend who comes to visit while in town for a wedding.

Courteney Cox

A few years after Friends came to an end and a few months before Cougar Town premiered, Courteney Cox had a brief fun on Scrubs. During her handful of appearances in the show’s eighth season, Cox played Dr. Taylor Maddox, the new Sacred Heart chief of medicine following Dr. Kelso’s (Ken Jenkins) sudden departure.

Dick Van Dyke

Probably the Scrubs celebrity guest with the most prolific career, Dick Van Dyke showed up for a single episode partway through the show’s second season. The legendary actor/singer/dancer took on the role of Dr. Doug Townshend, a Sacred Heart doctor who no longer wanted to stick around and keep up with technology and decided to retire.

Elizabeth Banks

In terms of guest spots, few actors appeared in as many episodes as Elizabeth Banks. Between Seasons 5 and 8, Banks popped up in a total of 15 episodes as Dr. Kim Briggs, a urologist at another hospital who eventually became the mother of J.D.’s son before it was all said and done.

Colin Farrell

Colin Farrell was just about everywhere in the 2000s, including Scrubs. The In Bruges actor played Billy Callahan, an Irishman who was sticking around to watch over a man he knocked out in a bar fight, partway through Season 4. Though his arrival caused a stir at Sacred Heart, it all eventually worked out in the end.

Aziz Ansari

Before he became one of the biggest comedians on the planet thanks to Parks and Recreation and Master of None, Aziz Ansari had a supporting role on Scrubs. Ansari appeared throughout the show’s eighth season where he played Dr. Ed Dhandapani, one of J.D.’s young interns, and possibly the laziest person at Sacred Heart.

Heather Graham

A major player throughout Scrubs Season 4, Heather Graham took on the role of Dr. Molly Clock, a psychiatrist at Sacre Heart who kept referring to J.D. as “Johnny.” She appeared in nine episodes during her single-season run on the show.

Billy Dee Williams

Billy Dee Williams, of Star Wars and Brian’s Song fame, showed up in a single episode of Scrubs Season 5. But like other guest stars, Williams played himself, or at least a version that was Julie Quinn’s (Mandy Moore) godfather.

Matthew Perry

The late Matthew Perry (appearing alongside his real-life father, John Bennett Perry) showed up for an episode of Scrubs back in the show’s fourth season. In his one-off appearance, Perry played Murray Marks, a man who comes to Sacred Heart Hospital to donate a kidney to his ailing father.

Mandy Moore

Several years before she led another all-time great NBC series, This Is Us, Mandy Moore showed up on Scrubs as Julie Quinn. Though she only appeared on a pair of episodes during the show’s fifth season, Moore’s character made quite an impact on the staff at Sacred Heart, especially J.D. Their romance was short-lived, but one the hopeless romantic doctor wouldn’t forget.

Richard Kind

Harvey Corman is definitely one of the most iconic (and annoying) guest characters on Scrubs, and that’s all thanks to the brilliant work by Richard Kind. A hypochondriac like no other, Corman was in and out of Sacred Heart Hospital with all kinds of issues and medical emergencies throughout Seasons 2 through 4.

Masi Oka

Before having a massive breakout role on Heroes, Masi Oka appeared on Scrubs off and on between Seasons 1 and 4, in which he took on the role of a lab tech named Franklyn. Though he only appeared in a handful of episodes before leaving the show, Oka’s character showed up in some of the most memorable moments in Scrubs history.

Tom Cavanagh

In addition to leading the comedy series Ed, Tom Cavanagh also had a sizable guest spot on Scrubs. Every once in a while, Cavanagh would show up as J.D.’s older brother, Dan Dorian. There for a life, a shoulder to cry on, or an important life lesson, Dan was there for some of his brother’s most trying moments.

Tara Reid

Tara Reid was part of the Scrubs cast for 11 episodes, with all but one coming from the show’s third season. During her run, Reid took on the role of Danni Sullivan, Ben Sullivan’s younger sister, who became one of J.D.’s many girlfriends at one point.

Phill Lewis

Phill Lewis has appeared just about everywhere throughout his prolific TV career, including Sacred Heart Hospital for a stretch. During his run on Scrubs, Lewis portrayed Hooch, an orthopedic surgeon with a wild and dangerous side, to say the very least.

Jason Bateman

Jason Bateman popped up for a single episode of Scrubs during the show’s fifth season. During his one-off appearance, Bateman plays Mr. Sutton, a garbageman who refuses to thank J.D. after being treated.

John Ritter

The late John Ritter showed up in two episodes of Scrubs as Sam Dorian, J.D.’s dad. The cash-strapped and constantly unemployed character had his issues, but still cared deeply for his song.

Taran Killam

Before landing a steady gig on Saturday Night Live, Taran Killam had a recurring role on Scrubs during the show’s penultimate season. Killam took on the role of Jimmy, one of J.D.’s interns at Sacred Heart.

Jimmie Walker

Jimmie Walker, best known for his portrayal of J.J. Evans and his “Dynomite” catchphrase from Good Times, appeared in two episodes of Scrubs. During the show’s first season, Walker played himself as he appeared in two of the J.D.’s signature daydreams.

Sean Hayes

Best known for his roles as Jack McFarland on Will & Grace, Sean Hayes has made a ton of other appearances over the years. This includes Scrubs, where he played Nick Murdoch, an intern whose time at Sacred Heart was shortlived because he couldn’t handle the stress and emotional toll of watching a young patient’s slow demise under his care.

Ricky Schroder

Ricky Schroder’s career got off to a hot start as a child actor, including multiple appearances and a leading role on Silver Spoons, one of the most beloved sitcoms of the ‘80s. That career would continue well into adulthood for the former teenage star, including a four-episode turn on Scrubs. During the show’s second season, Schroder played Paul Flower, a male nurse Elliott Reid (Sarah Chalke) was embarrassed to admit she was dating.

Kelli Williams

If you look at the list of the best TV shows of all time, you’ll find multiple featuring the work of Kelli Williams. In addition to Law & Order, Quantum Leap, The Practice, and Ally McBeal, there’s also Scrubs. During her two episodes back in 2001, Williams played Kristen Murphy, a surgical student at Sacred Heart Hospital.

Cheryl Hines

In the middle of her run as Larry David’s wife on Curb Your Enthusiasm, Cheryl Hines made a brief appearance on Scrubs. During a single episode in the show’s fifth season, Hines played Paige Cox, Dr. Perry Cox’s very religious sister who shows up at Sacred Heart Hospital and forces the temperamental doctor to think about memories he long locked away in the deepest and most secure vaults of his mind.

Dave Foley

Dave Foley, best known for his time on The Kids in the Hall and movies like A Bug’s Life and Toy Story 2, had a pair of appearances on Scrubs during the middle of the show’s nine-season run. Foley took on the role of Dr. Lester Hedrick, a Sacred Heart grief counselor who was like a softer, kinder, and more easy-going mentor for J.D. when compared to the easily angered and annoyed Dr. Cox.

Julianna Margulies

E.R. wasn’t the only NBC-based show set in a hospital to feature the work of Julianna Margulies, as she also popped up on Scrubs for a couple of episodes during the show’s fourth season. But instead of playing a doctor this time, Margulies took on the role of Jenna Broderick, a candidate for the scariest lawyer award. The malpractice attorney had a habit of showing up and causing trouble, especially with J.D. Not much is known about the character’s whereabouts about J.D. put an end to things.

Keri Russell

Keri Russell, best known for her work on shows like Felicity and The Americans, had a short run on Scrubs, appearing in two episodes. In the show’s sixth season, Russell took on the role of Melody O’Harra, Elliott’s sorority sister who shows up and brings her easy-go-lucky personality and philosophy on life to the core group of the cast, but mostly J.D.

Heather Locklear

Heather Locklear added Scrubs to her long list of TV credits when she appeared for a pair of episodes during the show’s second season. During her time on the show, Locklear played Julie Keaton, a pharmaceutical rep who showed up at Sacred Heart Hospital to sell her company’s latest and greatest product. But she got more than she could chew when she started a relationship with Dr. Perry Cox, which provided a short-lived reprieve for everyone who had grown tired of his anger and outbursts while making rounds.

Christopher Meloni

Christopher Meloni played one of the most sadistic prisoners in the Oz cast as well as a dedicated and complicated detective on Law & Order: Special Victims Unit, but did you know he played a pediatrician on Scrubs? Well, that was the case for an episode during the show’s third season in which he played Dr. David Norris, Dr. Cox and Jordan Sullivan’s (Christa Miller) son’s pediatrician. Though a far stretch from his turn as Chris Keller on the landmark HBO series, Dr. Norris was still a wild card, to say the very least.

Amy Smart

Amy Smart showed up in movies like Varsity Blues, Road Trip, and The Butterfly Effect throughout the late ‘90s and early 2000s, but she also had quite a few TV appearances during that stretch of time. This included a spot on Scrubs as Jamie Moyer, aka “Tasty Coma Wife,” the wife of a car crash victim. This led to one of J.D.’s most ridiculous relationships on the series, which is saying something.

Nicole Sullivan

Mad TV star Nicole Sullivan appeared in a handful of episodes of Scrubs. Sullivan played Jill Tracy, a recurring troubled patient at Sacred Heart who made an impact on everyone she encountered, for better or worse. Her death, which ultimately led to one of the show’s most heartbreaking sequences (it features The Fray’s “How To Save a Life”), is one that had a massive impact on the medical staff for years to come.